<p>Antidiabetic activity enhancement in streptozotocin + nicotinamide–induced diabetic rats through combinational polymeric nanoformulation</p>
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Fibrinolytic activity of the retinae in streptozotocin-diabetic rats.
Fibrinolytic activity of the retinae in control and diabetic rats was assayed quantitatively in twenty male rats made diabetic by giving a single injection of streptozotocin. All these rats were killed at either 3 months or 12 months. Ten saline-injected rats and five rats treated with 3-0-methylglucose and streptozotocin served as controls. As the plasminogen activator activity in diabetic rat...
متن کاملSerum Antiotensin Converting Enzyme Activity in Streptozotocin-induced Diabetic Rats
It is well recognized that diabetes mellitus is associated with an increase in kidney size, in both humans and experimental animals (1,2). The morphologic changes that occur in diabetic organs have been best characterized in the kidney. Early in the course of diabetes, kidney cells undergo hypertrophy and, later on, hyperplasia (3). Recent evidence indicates a possible role for the renin-angiot...
متن کاملHypoglycemic Activity of Fumaria parviflora in Streptozotocin-Induced Diabetic Rats.
PURPOSE Fumaria parviflora Lam (Fumariaceae) has been used in traditional medicine in the treatment of several diseases such as diabetes. The present work was designed to evaluate the hypoglycaemic effects of methanolic extract (ME) of F. parviflora in normal and streptozotocin-induced diabetic rats. METHODS The rats used were allocated in six (I, II, III, IV, V and VI) experimental groups (n...
متن کاملComputation of In Vivo Antidiabetic Activity of Holarrhena Antidysenterica Seeds Extracts in Streptozotocin-Induced Diabetic Rats
Medicinal plants have curative properties due to the presence of various complex chemical compositions, which are found as secondary plant metabolites in one or more parts of the plant. The aim of this study was to compute the antidiabetic activity of Holarrhena antidysenterica seeds extract in streptozotocin-induced diabetic rats. The experimental protocol designed as animals were divided i...
متن کاملAntihyperglycemic activity of herb extracts on streptozotocin-induced diabetic rats.
We investigated the effects of herb extracts, Rhus verniciflua, Agrimonia pilosa, Sophora japonica, and Paeonia suffruticosa, on the lowering of blood glucose levels and thiobarbituric acid reactive substances (TBARS) in streptozotocin (STZ)-induced diabetic rats. After 4 weeks, oral administration of Rhus verniciflua extract (50 mg/kg) exhibited a significant decrease in blood glucose levels i...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2019
ISSN: 1178-2013
DOI: 10.2147/ijn.s205319